Facility Personnel

Kovriginsquare

Evgenii Kovrigin, Director

We are delighted to welcome Dr. Evgenii Kovrigin as the new Director of the Magnetic Resonance Research Center at Notre Dame and as an Associate Research Professor. Dr. Kovrigin joins us from Marquette University, bringing his over seventeen years of NMR experience.

Dr. Kovrigin’s expertise centers on NMR theory and data analysis, particularly for small molecules and proteins. He has also developed new research software packages for the analysis of NMR line shapes, specifically including LineShapeKin, LineShapeKin Simulation, and Integrative Data Analysis Platform (IDAP). He holds a Ph.D. in Chemistry from the Engelhardt Institute of Molecular Biology (Moscow, Russia) and completed postdoctoral training at the Institute of Protein Research (Russia), UT Southwest Medical Center, and Yale University.

Recent Papers

  • McShan, A.C., Natarajan, K., Kumirov, V.K., Flores-Solis, D., Jiang, J., Badstübner, M., Toor, J.S., Bagshaw, C.R., Kovrigin, E.L., Margulies, D.H., Sgourakis, N.G. "Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle" 2018 Nature Chemical Biology, 14 (8), pp. 811-820. DOI: 10.1038/s41589-018-0096-2
  • Shishina, A.K., Kovrigina, E.A., Galiakhmetov, A.R., Rathore, R., Kovrigin, E.L. "Study of Förster Resonance Energy Transfer to Lipid Domain Markers Ascertains Partitioning of Semisynthetic Lipidated N-Ras in Lipid Raft Nanodomains" 2018 Biochemistry, 57 (5), pp. 872-881. DOI: 10.1021/acs.biochem.7b01181​​​​​​​
  • Galiakhmetov, A.R., Kovrigina, E.A., Xia, C., Kim, J.-J.P., Kovrigin, E.L. "Application of methyl-TROSY to a large paramagnetic membrane protein without perdeuteration: 13C-MMTS-labeled NADPH-cytochrome P450 oxidoreductase" 2018 Journal of Biomolecular NMR, 70 (1), pp. 21-31. DOI: 10.1007/s10858-017-0152-3​​​​​​​
  • Shinya, S., Ghinet, M.G., Brzezinski, R., Furuita, K., Kojima, C., Shah, S., Kovrigin, E.L., Fukamizo, T. "NMR line shape analysis of a multi-state ligand binding mechanism in chitosanase" 2017 Journal of Biomolecular NMR, 67 (4), pp. 309-319. DOI: 10.1007/s10858-017-0109-6
  • Yang, S., Pattengale, B., Kovrigin, E.L., Huang, J. "Photoactive Zeolitic Imidazolate Framework as Intrinsic Heterogeneous Catalysts for Light-Driven Hydrogen Generation" 2017 ACS Energy Letters, 2 (1), pp. 75-80. DOI: 10.1021/acsenergylett.6b00540​​​​​​​
  • Kovrigina, E.A., Pattengale, B., Xia, C., Galiakhmetov, A.R., Huang, J., Kim, J.-J.P., Kovrigin, E.L. "Conformational States of Cytochrome P450 Oxidoreductase Evaluated by Förster Resonance Energy Transfer Using Ultrafast Transient Absorption Spectroscopy" 2016 Biochemistry, 55 (43), pp. 5973-5976. DOI: 10.1021/acs.biochem.6b00623

Correspondence

Department of Chemistry and Biochemistry
University of Notre Dame
Notre Dame, IN 46556
Phone: (574) 631-8359
Fax: (574) 631-6652
Email: ekovrigu@nd.edu

 


Justin Pontius

Justin Pontius, Research Specialist

Justin Pontius, Research Specialist, joined the NMR team at Notre Dame in 2011. His major responsibilities include maintenance of all NMR systems, user familiarization and training. He has a wide range of experience in communication systems that utilize radar and digital radio technology.

Justin joined the US Navy in 2000 and was trained as an Electronics Technician, specializing in radar and communications at the Great Lakes Naval Training Center.  After graduation in 2001, he was assigned to the guided missile destroyer USS John S. McCain (DDG-56), where he maintained all shipboard external communication systems, radars, and TV/radio systems.  In 2005, Justin was reassigned to Tactical Training Group Pacific in San Diego, Calif., and led a team of nine personnel installing and maintaining analog and digital radio systems that linked San Diego, Washington, Hawaii, and Japan.  In 2007, he was sent to a forward operation base in Ethiopia to provide communications for a remote Seabee team building schools and digging wells during Operation Enduring Freedom.  He also provided onboard satellite communications for the Marine Heavy Helicopter Squadron 461, flying in CH-53E Super Stallion helicopters.  In early 2008, Justin left the navy to start a career with JEOL USA Inc.  There he installed, maintained and troubleshot all variants JEOL NMR systems.

Correspondence

Department of Chemistry and Biochemistry
University of Notre Dame
Notre Dame, IN 46556 

Phone: (574) 631-7601 
Fax: (574) 631-6652
Email: jpontius@nd.edu